Systematic review of excess mortality in India during the Covid-19 pandemic with differentiation between model-based and data-based mortality estimates

Background: COVID-19 has proven to be the worst pandemic in the history of mankind.While the pandemic still continues to perplex scientists globally, attempts are being made to quantify the mortality caused by the pandemic.Official COVID-19 figures in India grossly understate the true scale of the pandemic in the country.Fatality rates help us unde

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Dopamine Reduces SARS-CoV-2 Replication In Vitro through Downregulation of D2 Receptors and Upregulation of Type-I Interferons

Recent evidence suggests that SARS-CoV-2 hinders immune responses via dopamine (DA)-related mechanisms.Nonetheless, studies addressing the specific role of DA in the frame of SARS-CoV-2 infection are still missing.In the present study, we investigate the role of DA in SARS-CoV-2 replication along with potential links with innate immune pathways in

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